Christiane Fernandes Horn Email: Escritório: Sala 209 Laboratório: LIQIMeC (Lab 212) Fone Sala: (48) 3721-3619    http://lattes.cnpq.br/5377483143596229   0000-0003-0980-1798   O-1424-2017
LIQIMeC (Laboratório Interdisciplinar de Química Inorgânica Medicinal e Catálise)

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Área de Concentração: Química Inorgânica

Linhas de Pesquisa:

• BIOINORGÂNICA
• CATÁLISE
• COMPOSTOS DE COORDENAÇÃO
• SÍNTESE E REATIVIDADE DE COMPLEXOS INORGÂNICOS

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Publicações Selecionadas

1. Guerreiro JF, Gomes MAGB, Pagliari F, Jansen J, Marafioti MG, Nistico C, Hanley R, Costa RO, Ferreira SS, Mendes F, Fernandes C, Horn A, Tirinato L, Seco J. Iron and copper complexes with antioxidant activity as inhibitors of the metastatic potential of glioma cells. RSC Adv. 2020 Mar 30;10(22):12699-12710. doi: 10.1039/d0ra00166j. PMID: 35492123; PMCID: PMC9051468
2. Menezes LB, Segat BB, Tolentino H, Pires DC, Mattos LMM, Hottum HM, Pereira MD, Latini A, Horn A Jr, Fernandes C. ROS scavenging of SOD/CAT mimics probed by EPR and reduction of lipid peroxidation in S. cerevisiae and mouse liver, under severe hydroxyl radical stress condition. J Inorg Biochem. 2023 Feb;239:112062. doi: 10.1016/j.jinorgbio.2022.112062. Epub 2022 Nov 5. PMID: 36403436.
3. n vitro anti-Leishmania activity of new isomeric cobalt(II)complexes and in silico insights: mitochondria impairment and apoptosis-like cell death of the parasite. Samuel M. Rocha, Adolfo Horn Jr, Aline R. de M. L. Terra, Lara M. Rezende, Felipe F. Moreira, Renato A. DaMatta, Fernando R. Xavier, Rodrigo Cervo, Roberta Cargnelutti, Sreerag N. Moorkkannur, Graysen Owenby, Rajeev Prabhakar, Sérgio H. Seabra, Christiane Fernandes. Journal of Inorganic Biochemistry, 2023, 240, 112088. DOI:https://doi.org/10.1016/j.jinorgbio.2022.112088
4. A multipurpose metallophore and its copper complexes with diverse catalytic antioxidant properties to deal with metal and oxidative stress disorders:  A combined experimental, theoretical and in vitro study. Lucas Menezes, Raquel Sampaio,  Lino Meurer, Bruno Szpoganicz, Rodrigo Cervo, Roberta Cargnelutti, Lukun Wang, Jiawen Yang, Rajeev Prabhakar, Christiane Fernandes and Adolfo Horn. Inorganic Chemistry, 2024, 63, 32, 14827–14850. DOI: https://doi.org/10.1021/acs.inorgchem.4c00232
5. Maria E. Cirino, Thainá R. Teixeira, Alessandro M. H. Silva, Ana C. C. Borges, Lucas Fukui-Silva, Luis G. Wagner, Christiane Fernandes, Malachy McCann, André L. S. Santos, Josué de Moraes. Anthelmintic activity of 1,10-phenanthroline-5,6-dione-based metallodrugs. Sci Rep 15, 4699 (2025). https://doi.org/10.1038/s41598-025-88484-5