Josiel Barbosa Domingos Email: Escritório: Sala 202 Laboratório: LaCBio (303) Fone Sala: (48) 3721-3620 Fone Lab: (48) 3721-6570     http://lattes.cnpq.br/5962881646282175    0000-0002-6001-4522   I-7870-2013

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Linhas de Pesquisa

• BIOLOGIA QUÍMICA
• CATÁLISE

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Publicações Selecionadas

• Mechanistic Insights into Chloride-Dependent Uncaging Reaction of Propargyl and Allene-Protected Substrates by Pd-Complexes. CHEMISTRY-A EUROPEAN JOURNAL, v. 31, p. e202403987, 2025. http://dx.doi.org/10.1002/chem.202403987
• Interplay of chloride levels and palladium( ii )-catalyzed O -deallenylation bioorthogonal uncaging reactions. CHEMICAL SCIENCE, v. 15, p. 4458-4465, 2024. http://dx.doi.org/10.1039/d3sc06408e
• Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C-C Bond Cleavage Reactions. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v. 145, p. 10790-10799, 2023. http://dx.doi.org/10.1021/jacs.3c01960
• Controlled In-Cell Generation of Active Palladium(0) Species for Bioorthogonal Decaging. ANGEWANDTE CHEMIE, v. 61, p. e202113519, 2022. https://doi.org/10.1002/anie.202113519
• Mechanistic insights into transition metal-mediated bioorthogonal uncaging reactions. CHEMICAL SOCIETY REVIEWS, v. 49, p. 7710-7729, 2020. http://dx.doi.org/10.1039/d0cs00630k
• Platinum-triggered Bond-cleavage of Pentynoyl amide and N-propargyl handles for Drug-Activation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v. 142, p. 10869-10880, 2020. http://dx.doi.org/10.1021/jacs.0c01622
• On the mechanism of palladium(II)-mediated uncaging reactions of propargylic substrates. ACS CATALYSIS, v. 9, p. 3792-3799, 2019. http://dx.doi.org/10.1021/acscatal.9b00210
  

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